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Immunohistochemistry (IHC) is the most common application of immunostaining. It involves the process of selectively identifying antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues. IHC takes its name from the roots "immuno", in reference to antibodies used in the procedure, and "histo", meaning tissue (compare to immunocytochemistry). Albert Coons conceptualized and first implemented the procedure in 1941.
Visualising an antibody-antigen interaction can be accomplished in a number of ways, mainly either of the following:
Chromogenic immunohistochemistry (CIH), wherein an antibody is conjugated to an enzyme, such as peroxidase (the combination being termed immunoperoxidase), that can catalyse a colour-producing reaction.Immunofluorescence, where the antibody is tagged to a fluorophore, such as fluorescein or rhodamine.Immunohistochemical staining is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors. Specific molecular markers are characteristic of particular cellular events such as proliferation or cell death (apoptosis).Immunohistochemistry is also widely used in basic research to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of a biological tissue.
reference| Full Form | Category |
|---|---|
| Interdepartmental Hurricane Conference | Academic & Science |
| Immuno Histo Chemical | Academic & Science |
| International Harvester Company | Business |
| International Harvester Corporation | Business |
| India Hsp Di | Business |
| Independence Holding Company | Business |
| International Harvester Corp | Business |
| Immunohistochemistry | Chemistry |
| Interchurch Holiness Convention | Community |
| Islamic Heritage Center | Community |
| Intelligent House Control | Computing |
| Inflation Hedging Coin | Cryptocurrency |
| International Hockey College | Educational Institute |
| Intelligent Headlight Controller | General |
| Industrial Hearing Compensation | General |
| Italia Hummer Club | General |
| Integrated Headset Compression | General |
| Illiana Hummer Club | General |
| Intake Heat Control | General |
| In Home Care | General |
| Interagency Hotshot Crews | General |
| Improving His Claim | General |
| In His Care | General |
| Internal Hidden Compression | General |
| Integral Handling Control | General |
| Interlectually Handicapped Children | General |
| In Holland Clan | General |
| Im Hard Core | General |
| Indian Head Cent | General |
| Interstate Highway Construction | General |
| Inner Hair Cells | General |
| I Heart Chaos | General |
| Interdisciplinary Humanities Center | General |
| I Hate Competition | General |
| Hobby com | General |
| Immaculate Heart Central | General |
| Intelligent Headlamp Control | General |
| International Hill Climb | General |
| Islamabad High Court | Governmental |
| Inland Haulauge Charge | Governmental |
| Idaho Humanities Council | Governmental |
| Inter Hall Council | Governmental |
| Illinois Housing Council | Governmental |
| Inland Haulage Charges | Governmental |
| Institute for Human Continuity | Governmental |
| Industrial Health Council | Governmental |
| Illinois Humanities Council | Governmental |
| Iowa Healthcare Collaborative | Healthcare |
| Indianapolis Hebrew Congregation | International |
| International Hobby Corporation | International |
| International Hapkido Corporation | International |
| Long term health | Medical |
| Institute for Healthcare Communication | Medical |
| Intermountain Health Care | Medical |
| Institute for HealthCare Consumerism | Medical |
| Imperial High Command | Military and Defence |
| International Humanitarian Community | Military and Defence |
| IHC Industry | Regional |
Posted on 28 Apr 2022, this text provides information on Miscellaneous in Chemistry related to Chemistry. Please note that while accuracy is prioritized, the data presented might not be entirely correct or up-to-date. This information is offered for general knowledge and informational purposes only, and should not be considered as a substitute for professional advice.
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