AAPC meaning in Medical ?

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What is Antibiotic Associated Pseudomembranous Colitis mean?

Clostridioides difficile infection (CDI or C-diff), also known as Clostridium difficile infection, is a symptomatic infection due to the spore-forming bacterium Clostridioides difficile. Symptoms include watery diarrhea, fever, nausea, and abdominal pain. It makes up about 20% of cases of antibiotic-associated diarrhea. Antibiotics can contribute to detrimental changes in gut microbiota; specifically, they decrease short-chain fatty acid absorption which results in osmotic, or watery, diarrhea. Complications may include pseudomembranous colitis, toxic megacolon, perforation of the colon, and sepsis.

Clostridioides difficile infection is spread by bacterial spores found within feces. Surfaces may become contaminated with the spores with further spread occurring via the hands of healthcare workers. Risk factors for infection include antibiotic or proton pump inhibitor use, hospitalization, other health problems, and older age. Diagnosis is by stool culture or testing for the bacteria's DNA or toxins. If a person tests positive but has no symptoms, the condition is known as C. difficile colonization rather than an infection.

Prevention efforts include terminal room cleaning in hospitals, limiting antibiotic use, and handwashing campaigns in hospitals. Alcohol based hand sanitizer does not appear effective. Discontinuation of antibiotics may result in resolution of symptoms within three days in about 20% of those infected. The antibiotics metronidazole, vancomycin or fidaxomicin, will cure the infection. Retesting after treatment, as long as the symptoms have resolved, is not recommended, as a person may often remain colonized. Recurrences have been reported in up to 25% of people. Some tentative evidence indicates fecal microbiota transplantation and probiotics may decrease the risk of recurrence.

C. difficile infections occur in all areas of the world. About 453,000 cases occurred in the United States in 2011, resulting in 29,000 deaths. Global rates of disease increased between 2001 and 2016. C. difficile infections occur more often in women than men. The bacterium was discovered in 1935 and found to be disease-causing in 1978. In the United States, healthcare-associated infections increase the cost of care by US$1.5 billion each year. Although C. difficile is a common healthcare-associated infection, at most 30% of infections are transmitted within hospitals. The majority of infections are acquired outside of hospitals, where medications and a recent history of diarrheal illnesses (e.g. laxative abuse or food poisoning due to Salmonellosis) are thought to drive the risk of colonization.

reference
Full Form Category
Admissions and Academic Policies Committee Academic & Science
Academic Advancement and Promotions Committee Academic & Science
Academic Affairs Planning Committee Academic & Science
Association des Architectes Paysagistes du Canada Academic & Science
Canadian Society of Landscape Architects Academic & Science
American Academy of Professional Codes Academic & Science
Academic Admissions Policy Committee Academic & Science
Academic and Performance Center Academic & Science
American Architectural Products, Incorporated (de-listed) Business
American Association of Paging Carriers Business
Atlantic Alliance Partnership Corp Business
Autism Asperger Publishing Company Business
African-American Parent Coalition Community
Annual Agricultural Policy Conference Community
American Association of Pastoral Counselors Community
American Academy of Professional Coders Community
American Association of Professional Coders Community
Advanced Armored Personnel Carrier General
Asociacion Argentina de Propietarios de Camiones General
Average Annual Percent Change General
An Ambitious Project Collapsing General
Attenuated Adenomatous Polyposis Coli General
Accounting and Auditing Policy Committee Governmental
Area Agency Program Coordinator Governmental
Advanced Armoured Personnel Carrier Governmental
American Association of Political Consultants Governmental
American Automotive Policy Council Governmental
Army Acquisition Professionals Course Governmental
Antibiotic Associated Pseudomembranous Colitis Medical
Artificial Antigen Presenting Cell Medical
Aviation Accident Prevention Course Medical
African Auxiliary Pioneer Corps Regional
All-African Peoples' Conference Regional
Australian Army Pay Corps Regional
Australian Army Provost Corps Regional
African American Professionals Conference Regional

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Posted on 22 Dec 2024, this text provides information on Miscellaneous in Medical related to Medical. Please note that while accuracy is prioritized, the data presented might not be entirely correct or up-to-date. This information is offered for general knowledge and informational purposes only, and should not be considered as a substitute for professional advice.

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