CAP meaning in Medical ?

Answer:

What is Catabolite Activator Protein mean?

Catabolite activator protein (CAP; also known as cAMP receptor protein, CRP) is a trans-acting transcriptional activator that exists as a homodimer in solution. Each subunit of CAP is composed of a ligand-binding domain at the N-terminus (CAPN, residues 1-138) and a DNA-binding domain at the C-terminus (DBD, residues 139-209). Two cAMP (cyclic AMP) molecules bind dimeric CAP with negative cooperativity. Cyclic AMP functions as an allosteric effector by increasing CAP's affinity for DNA. CAP binds a DNA region upstream from the DNA binding site of RNA Polymerase. CAP activates transcription through protein-protein interactions with the α-subunit of RNA Polymerase. This protein-protein interaction is responsible for (i) catalyzing the formation of the RNAP-promoter closed complex; and (ii) isomerization of the RNAP-promoter complex to the open conformation. CAP's interaction with RNA polymerase causes bending of the DNA near the transcription start site, thus effectively catalyzing the transcription initiation process. CAP's name is derived from its ability to affect transcription of genes involved in many catabolic pathways. For example, when the amount of glucose transported into the cell is low, a cascade of events results in the increase of cytosolic cAMP levels. This increase in cAMP levels is sensed by CAP, which goes on to activate the transcription of many other catabolic genes.

CAP has a characteristic helix-turn-helix motif structure that allows it to bind to successive major grooves on DNA. The two helices are reinforcing, each causing a 43° turn in the structure, with an overall 94° degree turn in the DNA.

This interaction opens up the DNA molecule, allowing RNA polymerase to bind and transcribe the genes involved in lactose catabolism. cAMP-CAP is required for transcription activation of the lac operon.

This requirement reflects the greater simplicity with which glucose may be metabolized in comparison to lactose. The cell "prefers" glucose, and, if it is available, the lac operon is not activated, even when lactose is present. This is an effective way of integrating the two different signals. This phenomenon is known as catabolite repression. CAP plays an important role in catabolite repression, a well-known example of a modulon and also plays a role in the Mal regulon.

reference

Full Form	Category
Calcium Phosphate	Academic & Science
College Access Program	Academic & Science
College of American Patholgists	Academic & Science
College Alumni Program	Academic & Science
Curricular Academic Program	Academic & Science
Computer Analysis Project	Academic & Science
Capital Academic Program	Academic & Science
Cumulative Average Point	Academic & Science
Campus Accountability Partner	Academic & Science
Campus Access Point	Academic & Science
Center for Applied Probability--Columbia University	Academic & Science
Centre for Academic Practice	Academic & Science
Clinical Advancement Program	Academic & Science
Career Advisory Program	Academic & Science
Contemporary Architecture Practice	Academic & Science
Circum-Atlantic Project	Academic & Science
Catabolic gene activator proteins	Academic & Science
College Alliance Program	Academic & Science
Center for Applied Probability	Academic & Science
Continuous Assessment Programme	Academic & Science
Competency Assessment Program	Accounts and Finance
Customer Approved Payment	Accounts and Finance
Cap Haitien	Airport Code
Capital	Banking
Carpentaria Exploration, LTD.	Business
Customer Availability Program	Business
Canadian Association of Paralegals (l?ssociation Canadienne des Parajuristes)	Business
Chip Authentication Program	Business
Certified Angel Practitioner	Business
Certified Authorization	Business
Communications Advertising and Public	Business
Canadian Association of Paralegals (l’Association Canadienne des Parajuristes)	Business
Canadian Association of Palynologists (Association Canadienne des Palynologues)	Business
Canadian Association of Physicists (Association Canadienne des Physiciens et Physiciennes)	Business
Commonwealth Association of Planners	Business
Consulting Architects and Planners	Business
Courtesy Awareness Programme	Business
Coordinating Agency Partner	Business
Change And Partnership	Business
Customer Appreciation Program	Business
Compliance Assurance Program	Business
Consistency Application And Professionalism	Business
Cover And Plinth	Business
Cost Avoidance Program	Business
Committee of Advertising Practice	Business
Client Appreciation Program	Business
Collected and Assessed Problem	Business
Competitive Advantage Period	Business
Certified Authorization Professional	Certifications
Certified Analytics Professional	Certifications
Communty Access Program	Community
Community Arts Partnership	Community
Coordination Actors And Production	Community
Content Acquisition Program	Community
Come And Pay	Community
Computer-Aided Publishing	Community
Community Access Program	Community
Children Awaiting Parents	Community
Community Access Project	Community
Christian Appalachian Project	Community
Cool Arizona Pets	Community
Charitable Annuity Program	Community
Client Assistance Program	Community
Community Action Plan	Community
Childcare Action Project	Community
Create A Park	Community
Community Alternatives Program	Community
Community Action Program	Community
Capping Anger Positively	Community
Community Advisory Panel	Community
Childcare Action Program	Community
Commune Action Plan	Community
Community Action Project	Community
Community Action Partnership	Community
Community Awareness Program	Community
Conservation Assessment Program	Community
Corrective Action Plan	Community
Creative Arts Program	Community
Chartered Advisor in Philanthropy	Community
Cooperative Advantage Program	Community
Community Awareness Campaign	Community
Center for American Progress	Community
Christians Against Poverty	Community
Community Access Programming	Community
Carrier-less Amplitude modulation Phase modulation	Computer and Networking
Compressed and Packed	Computer Assembly Language
Casing Added Protection	Computer Hardware
Computer Accommodations Program	Computing
Computer Aided Poetry	Computing
Computer Aided Principle	Computing
Computer Aided Policing	Computing
Computer Aided Procurement	Computing
Computer Aided Painting	Computing
Computer Assisted Programming	Computing
Computer Aided Production	Computing
Computer Aided Prognosis	Computing
Computer Aided Pets	Computing
Computer Aided Positioner	Computing
Computer Aided Probing	Computing
Computer Aided Program	Computing
Computer Aided Preparation	Computing
Cloudbees Assurance Program	Computing
Cloud Access Point	Computing
Computer Assisted Purchasing	Computing
Current Applications Presentation	Computing
Cut And Paste	Computing
Computer And Printer	Computing
Client Allocation Protocol	Computing
Ctm Access Profile	Computing
Computer Aided Printing	Computing
Commercial Access Provider	Computing
Capture File	Computing
Calendar Access Protocol	Computing
Configuration Access Protocol	Computing
Connection Approval Program	Computing
Carrierless Amplitude and Phase	Computing
Customer Access Program	Computing
Connector Application Pack	Computing
Compaq Accredited Professional	Computing
Computer Aided Planning	Computing
Canon Advanced Printing	Computing
Course Authoring Package	Computing
Capitalized Phrase	Computing
Computer Aided Parallelization	Computing
Cartridge Access Port	Computing
Common Application Platform	Computing
Camel Application Part	Computing
Certification and Accreditation Program	Computing
Chip Authentication Programme	Computing
Certified Access Point	Computing
Change Application Procedure	Computing
Certified Advantage Partner	Computing
Computer Acquisition Program	Computing
Certified Advanced Professional	Computing
Controlled Access Phase	Computing
Current Active Position	Computing
Customer Administration Panel	Computing
Computer Automated Programming	Computing
Communicating Applications Platform	Computing
Cyber Asset Protection	Computing
Cyber Awareness Program	Computing
Cybersecurity Assurance Program	Computing
Connection Approval Process	Computing
Capital.Finance	Cryptocurrency
Consistency, Availability, and Partition	Database Management
Carrierless Amplitude Phase	Electronics
Capacitor	Electronics
Combined Analog and Pulsative	Electronics
Ventura Publisher Caption File	File Type
Compressed Music File	File Type
Session Capture File (procomm - Telix)	File Type
Clean Air Power	General
Caravan Allowable Payload	General
Collision Avoidance Processor	General
Chrome Appearance Package	General
Career Automotive Program	General
Change Acceleration Process	General
China Auto Parts	General
Cold Ambient Protection	General
Club Alpine de Picardie	General
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Carwash Association of Pennsylvania	General
College Automotive Program	General
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Canadian Auto Press	General
Certified Aftermarket Parts	General
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Child Access Prevention	General
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Collective Advocacy Project	General
Center for the Art of Performance	General
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Chinky And Pinky	General
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Color Additive Petition	Governmental
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Caput	International
Create A Pokemon	Internet
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clinical articulation profile?peech	Medical
Cyclase Activating Pth	Medical
College Of American Pathologists	Medical
Community-acquired pneumonia	Medical
Chronic Apical Periodontitis	Medical
calcium-to-phosphorus–ratio	Medical
Canadian Association of Pathologists	Medical
cancer of prostate	Medical
capillaries	Medical
capitation	Medical
capsaicin	Medical
captopril	Medical
carbamyl phosphate	Medical
carcinoma of prostate	Medical
Cationic Activator Protein	Medical
Cell Attachment Protein	Medical
Center Accreditation Project	Medical
Child Abuse Potential	Medical
Children of Alcoholic Parents	Medical
cholesteric analysis profile test	Medical
Chronic Alcoholic Pancreatitis	Medical
Clathrin-Associated Protein	Medical
clinical articulation profile–speech	Medical
Common Assurance Process	Medical
Community Access Programme	Medical
Compliance Aid for Pharmaceuticals	Medical
Compound Action Potential	Medical
computerised automated psychophysiological device	Medical
Cost Alocation Procedure	Medical
Council on Alcohol Policy	Medical
Criteria Air Pollutant	Medical
Cyclase-Activating Protein	Medical
cyclic AMP	Medical
cyclophosphamide, Adriamycin, prednisone	Medical
cystine aminopeptidase	Medical
cystylaminopeptidase	Medical
Camptodactyly Arthropathy Pericarditis	Medical
calcium-to-phosphorus?atio	Medical
Capsule	Medical
Cognitive Affective And Physical	Medical
Central Auditory Processing	Medical
Cooperative of American Physicians	Medical
CAPsula (CAPsule)	Medical
Catabolite Activator Protein	Medical
Cytoskeleton Associated Proteins	Medical
Cationic Antimicrobial Peptide	Medical
Civil Augmentation Program	Military and Defence
Consolidated Appeals Process	Military and Defence
Crisis Action Planning	Military and Defence
Captain [mil.]	Military and Defence
Crisis Action Procedures	Military and Defence
Configuration Audit Plan	Military and Defence
Capability	Military and Defence
Combat Air Patrol	Military and Defence
Current Approved Program	Military and Defence
Configuration and Alarm Panel	Military and Defence
Columbia Appletalk Package	Networking
Client Access Protocol	Networking
Competitive Access Provider	Networking
Congress of Aboriginal Peoples	Regional
National Coalition Against the Privatization of Water	Regional
Common Aftermarket Protocol	Softwares
Collaborative Analytical Processing	Softwares
Custom Application Program	Softwares
Channel Assembly Program	Softwares
Capacity	Space Science
Ccms (checkout, Control and Monitor System) Application Program	Space Science
Computer Application Program	Space Science
Contractor Acquired Property	Space Science
Cost Account Package	Space Science
Crew Activity Plan	Space Science
Celebration of Athletic Participation	Sports
Hugo Chavez International Airport	Transport & Travel