CLCD meaning in Medical ?

Answer:

What is Cleidocranial Dysostosis mean?

Cleidocranial dysostosis (CCD), also called cleidocranial dysplasia, is a birth defect that mostly affects the bones and teeth. The collarbones are typically either poorly developed or absent, which allows the shoulders to be brought close together. The front of the skull often does not close until later, and those affected are often shorter than average. Other symptoms may include a prominent forehead, wide set eyes, abnormal teeth, and a flat nose. Symptoms vary among people; however, intelligence is typically unaffected.

The condition is either inherited from a person's parents or occurs as a new mutation. It is inherited in an autosomal dominant manner. It is due to a defect in the RUNX2 gene which is involved in bone formation. Diagnosis is suspected based on symptoms and X-rays with confirmation by genetic testing. Other conditions that can produce similar symptoms include mandibuloacral dysplasia, pyknodysostosis, osteogenesis imperfecta, and Hajdu-Cheney syndrome.

Treatment includes supportive measures such as a device to protect the skull and dental care. Surgery may be performed to fix certain bone abnormalities. Life expectancy is generally normal.

It affects about one per million people. Males and females are equally commonly affected. Modern descriptions of the condition date to at least 1896. The term is from cleido meaning collarbone, cranial from the Greek κρανιὀς meaning skull, and dysostosis meaning formation of abnormal bone.

reference

Full Form	Category
Children's Literature Comprehensive Database	Academic & Science
Center for Leadership, Citizenship and Democracy (University of the Philippines-Diliman)	Academic & Science
Centre for Learning, Change and Development (Murdoch University; Australia)	Academic & Science
Center for Leadership, Citizenship and Democracy	Community
Contemporary Life Cycle Development	Community
Color Lcd	Computing
Chinese Life Cycle Database	Computing
Cleidocranial Dysplasia	Medical
Cleidocranial Dysostosis	Medical