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What is Field Flow Fractionation mean?
Field-flow fractionation, abbreviated FFF, is a separation technique which does not have a stationary phase. It is similar to liquid chromatography as it works on dilute solutions or suspensions of the solute. Separation is achieved by applying a field (hydraulic, centrifugal, thermal, electric, magnetic, gravitational, ...) perpendicular to the direction of transport of the sample which is pumped through a long and narrow channel. The field exerts a force on the sample components concentrating them towards one of the channel walls, which is called accumulation wall. The force interacts with a property of the sample on which then the separation occurs, in other words on their differing "mobilities" under the force exerted by the field. As an example, for the hydraulic, or cross-flow FFF method, the property driving separation is the translational diffusion coefficient or the hydrodynamic size. For a thermal field (heating one wall and cooling the other), it is the ratio of the thermal and the translational diffusion coefficient.
referencePosted on 26 Oct 2024, this text provides information on Miscellaneous in Physics Related related to Physics Related. Please note that while accuracy is prioritized, the data presented might not be entirely correct or up-to-date. This information is offered for general knowledge and informational purposes only, and should not be considered as a substitute for professional advice.
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