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What is Hardy Weinberg mean?
In population genetics, the Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences. These influences include genetic drift, mate choice, assortative mating, natural selection, sexual selection, mutation, gene flow, meiotic drive, genetic hitchhiking, population bottleneck, founder effect and inbreeding.
In the simplest case of a single locus with two alleles denoted A and a with frequencies f(A) = p and f(a) = q, respectively, the expected genotype frequencies under random mating are f(AA) = p2 for the AA homozygotes, f(aa) = q2 for the aa homozygotes, and f(Aa) = 2pq for the heterozygotes. In the absence of selection, mutation, genetic drift, or other forces, allele frequencies p and q are constant between generations, so equilibrium is reached.
The principle is named after G. H. Hardy and Wilhelm Weinberg, who first demonstrated it mathematically. Hardy's paper was focused on debunking the view that a dominant allele would automatically tend to increase in frequency (a view possibly based on a misinterpreted question at a lecture). Today, tests for Hardy–Weinberg genotype frequencies are used primarily to test for population stratification and other forms of non-random mating.
referencePosted on 03 Oct 2024, this text provides information on Miscellaneous in General related to General. Please note that while accuracy is prioritized, the data presented might not be entirely correct or up-to-date. This information is offered for general knowledge and informational purposes only, and should not be considered as a substitute for professional advice.
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