OPG meaning in Medical ?

Answer: What is Osteoprotegerin mean?

Osteoprotegerin (OPG), also known as osteoclastogenesis inhibitory factor (OCIF) or tumour necrosis factor receptor superfamily member 11B (TNFRSF11B), is a cytokine receptor of the tumour necrosis factor (TNF) receptor superfamily encoded by the TNFRSF11B gene.

OPG was first discovered as a novel secreted TNFR related protein that played a role in the regulation of bone density and later for its role as a decoy receptor for Receptor Activator of Nuclear Factor kappa-B ligand (RANKL). OPG also binds to TNF-related apoptosis-inducing ligand (TRAIL) and inhibits TRAIL induced apoptosis of specific cells, including tumour cells. Other OPG ligands include syndecan-1, glycosaminoglycans, von Willebrand Factor, and Factor VIII-von Willebrand Factor complex.

OPG has been identified as having a role in tumour growth and metastasis, heart disease, immune system development and signalling, mental health, diabetes, and the prevention of pre-eclampsia and osteoporosis during pregnancy.

reference

Full Form	Category
Office of Projects and Grants	Academic & Science
Ontario Power Generation	Business
Opg Power	Business
Online Policy Group	Community
Output Gain	Computing
Object Programmer's Guide	Computing
Operation Pet Game	General
Office of the Public Guardian	General
Organization Project Grants	General
of the Public Guardian	General
Original Parts Group	General
Office of Public Guardian	General
Oldroyd Publishing Group	General
Ontario Power Gen	General
Office of Problem Gambling	General
Order Processing Guideline	General
Outpatient Procedure Grouper	General
Official Pistol Gang	General
Organisms per Gram	General
Online Performers Group	General
Operations Proving Ground	General
Organizational Performance Group	General
Official Pricing Guide	General
Optical Parametric Generator	General
Oil Pressure Gauge	General
Occupant Protection Guards	General
Oil Pump Gasket	General
Orbital Police Guard	Governmental
Official Police Garage	Governmental
Operations Planning Group	Governmental
Official Police Garages	Governmental
Operations Planners Group	Governmental
Office Planning Group	Governmental
Osteoprotegerin	Medical
OrthoPantomoGram	Medical
ocular plethysmography	Medical
Office of the Paymaster General	Medical
oocysts per gram (of faeces)	Medical
Optic Pathway Glioma	Medical
OculoPlethysmoGraphy	Medical
OhioHealth Physician Group	Medical
Ogn, Papua New Guinea	Regional