Ph meaning in Medical ?

Answer:

What is Philadelphia Chromosome mean?

The Philadelphia chromosome or Philadelphia translocation (Ph) is a specific genetic abnormality in chromosome 22 of leukemia cancer cells (particularly chronic myeloid leukemia (CML) cells). This chromosome is defective and unusually short because of reciprocal translocation, t(9;22)(q34;q11), of genetic material between chromosome 9 and chromosome 22, and contains a fusion gene called BCR-ABL1. This gene is the ABL1 gene of chromosome 9 juxtaposed onto the breakpoint cluster region BCR gene of chromosome 22, coding for a hybrid protein: a tyrosine kinase signalling protein that is "always on", causing the cell to divide uncontrollably by interrupting the stability of the genome and impairing various signaling pathways governing the cell cycle.

The presence of this translocation is required for diagnosis of CML; in other words, all cases of CML are positive for BCR-ABL1. (Some cases are confounded by either a cryptic translocation that is invisible on G-banded chromosome preparations, or a variant translocation involving another chromosome or chromosomes as well as the long arm of chromosomes 9 and 22. Other similar but truly Ph-negative conditions are considered CML-like myeloproliferative neoplasms.) However, the presence of the Philadelphia (Ph) chromosome is not sufficiently specific to diagnose CML, since it is also found in acute lymphoblastic leukemia (aka ALL, 25–30% of adult cases and 2–10% of pediatric cases) and occasionally in acute myelogenous leukemia (AML) as well as mixed-phenotype acute leukemia (MPAL).

reference

Full Form	Category
Partition Height	Academic & Science
Hydrogen ion concentration (pH grade)	Academic & Science
Pale Headed	Academic & Science
Power/Potential of Hydrogen	Academic & Science
Plant Hygrophelia	Academic & Science
Psychological Hypnosis	Academic & Science
Potential Hydrogen	Academic & Science
Propane Heat	Business
Product Hierarchy	Business
Per Hire	Business
Parallel Haskell	Business
Power House	Business
Parker Hannifin Corporation	Business
Potential of Hydrogen	Chemistry
Public Health	Chemistry
Potassium Hydrogen	Chemistry
Pondus Hydrogenii	Chemistry
Probable Helium	Chemistry
Power of Hydrogen	Chemistry
Pubic Hair	Community
Permanent Hiatus	Community
Place Hold	Community
Public House	Community
Philippines (TLD)	Computing
Programming Humor	Computing
Perl Header	Computing
Public Html	Computing
Philippines	Country Names
Phone	Electronics
Geoworks Optimized .goh Include File	File Type
Perl Header File	File Type
Phrase-table (ms C/c++)	File Type
Potential Heat	General
Paul Halpern	General
Potenial Hydrogen	General
Pee Here	General
Poul Henningsen	General
Potenz Hydrogen	General
Precipitation Hardening	General
Pokemon Heart	General
Phi Hanh	General
Players Handbook	General
The Pulsed Heat	General
Phucking Huge	General
Physically Handicaped	General
Ping Hui	General
Punishment House	General
Potential Of Hardness	General
Platinum Hit	General
Place Holder	General
Phillips Head	General
Penthouse	General
PantyHose	General
Pocket Hole	General
Power of Hydronium	General
Partido Humanista	Governmental
Project Headquarters	Governmental
Public Holidays	Governmental
Polyphase	Governmental
Political Hypocrisy	Governmental
Phonetic spelling of word or name	Governmental
Philadelphia Field Office	Governmental
PANOH	Indian Railway Station
Parliament house Quota	Indian Railways
Pädagogische Hochschule	International
potentiel d'Hydrogène	International
Potentia Hydrogenii	International
Porn Hub	Internet
Party Hard	Internet
Professional Hunter	Jobs
Philadelphia Chromosome	Medical
Previous History	Medical
Pharmacies	Medical
Expression of Acidity Or Alkalinity	Medical
acidity (pH)	Medical
Papillary Hyperplasia	Medical
Parathyroid Hormone	Medical
Partial Hysterectomy	Medical
Passive Haemagglutination	Medical
Patient History	Medical
Peliosis Hepatis	Medical
phenacetin	Medical
Philadelphia	Medical
Pin Hole	Medical
Porphyria Hepatica	Medical
Posterior Hypothalamus	Medical
Postural Hypotension	Medical
Primary Hyperparathyroidism	Medical
Prolyl Hydroxylase	Medical
Prospect Hill	Medical
Pseudoepitheliomatous Hyperplasia	Medical
Pulmonary Haemorrhage	Medical
Pulmonary Haemosiderosis	Medical
Power of Hydrogen (hydrogen-ion concentration)	Medical
Past History	Medical
Hydrogen ion concentration	Medical
Potential Health	Medical
Presbyterian Hospital	Medical
Post-Hartshorne	Medical
Pleckstrin Homology	Medical
Process Homeostasis	Medical
Proportional Hazard	Military and Defence
Pulmonary Hypertension	Military and Defence
Purple Heart	Military and Defence
Private Header	Networking
Percentage Hydrogen	Physics Related
Prahova	Regional
Patch for Hp	Softwares
Hydrogen-ion Concentration (alkalinity)	Space Science
Personal Hygiene	Space Science
Phase	Space Science
Pinch Hitter	Sports
Prancing Horse	Sports