TCR meaning in Medical ?

Answer:

What is T-cell receptor mean?

The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR.

The TCR is composed of two different protein chains (that is, it is a hetero dimer). In humans, in 95% of T cells the TCR consists of an alpha (α) chain and a beta (β) chain (encoded by TRA and TRB, respectively), whereas in 5% of T cells the TCR consists of gamma and delta (γ/δ) chains (encoded by TRG and TRD, respectively). This ratio changes during ontogeny and in diseased states (such as leukemia). It also differs between species. Orthologues of the 4 loci have been mapped in various species. Each locus can produce a variety of polypeptides with constant and variable regions.

When the TCR engages with antigenic peptide and MHC (peptide/MHC), the T lymphocyte is activated through signal transduction, that is, a series of biochemical events mediated by associated enzymes, co-receptors, specialized adaptor molecules, and activated or released transcription factors. Based on the initial receptor triggering mechanism, the TCR belongs to the family of non-catalytic tyrosine-phosphorylated receptors (NTRs).

reference

Full Form	Category
Transformative Consumer Research	Academic & Science
Technical College of the Rockies	Academic & Science
The Climate Registry	Academic & Science
T Cell Receptors	Academic & Science
Toxic Chemical Remover	Academic & Science
Cornerstone Realty Income Trust I	Business
Thursday Club Recordings	Community
Tucker Creek Rabbitry	Community
The Club of Riverdale	Community
Theatre Cedar Rapids	Community
Tennis Club of Rochester	Community
Transnational Cultural Remittances	Community
Trammell Crow Residential	Community
The Computer Room	Computer Hardware
Technical Committee Reference	Computing
The Common Rule	Computing
True Color Reproduction	Computing
Transit Control Record	Computing
Task Change Request	Computing
Transient Call Record	Computing
Time Created	Computing
Test Command Response	Computing
Tagged Cell Rate	Computing
Text Compression for Reader	Computing
Timer Control Register	Computing
Transaction Conversion Rate	Computing
Tariff Comparison Rates	Computing
Tracer DAO	Cryptocurrency
TecraCoin (ERC20)	Cryptocurrency
Teachers College Record	Educational Institute
Temperature Coefficient of Resistance	Electronics
Traby Club Romania	General
Team Cobra Racing	General
Twin City Rodders	General
Tuning Club Romania	General
The Caesar Report	General
Transformational Challenge Reactor	General
Tinted Candy Reviews	General
Tig And Compact Road	General
The Color Red	General
The Corner Room	General
Temperature Compensated Refresh	General
Tsindos Car Rentals	General
Tabors Caramanis Rudkevich	General
Tile City Rural	General
The Crimson Retard	General
tal Coliform Rule	General
The Colbert Report	General
Triple Calendar Round	General
the Concord Review	General
Total Coliform Rule	General
Tip Complaint Or Referral	General
Translator Client Review	General
Technical Communication and Rhetoric	General
Tim Cameron Ryan	General
Time Code Reader	General
Tivoli Common Reporting	General
tal Choice Radio	General
Tournament Completion Ratio	General
Tactical Compact Rifle	General
Tom Clark Replica	General
Time Counter Reading	General
Time Code Reading	General
Temperature Controlled Radio	General
Tariff Comparison Rate	General
Temperature Coefficient Resistance	General
Triangle Cellular Repair	General
tal Cleaning and Restoration	General
tal Compact Road	General
Turbodiesel Common Rail	General
Tester Common Rail	General
Total Control Racing	General
Twin Cam Racing	General
Touring Competition Radiale	General
Technocentre Renault	General
Track Creator Racing	General
Traffic Congestion Reduction	General
Traffic Control Review	General
ttenham Court Road	Governmental
THRISUR	Indian Railway Station
Translational Cancer Research	Medical
Teenage Conception Rate	Medical
Texas Cancer Registry	Medical
Tornado Cleanup & Response	Medical
T-cell receptor	Medical
Twentieth Century Romeo	Messaging
Tactical Control Room	Military and Defence
Transfer Control Record	Military and Defence
Test Completion Report	Military and Defence
Tottenham Court Road (in London)	Regional
Test Compare Results	Space Science
Test Constraints Review	Space Science
Thermal Concept Review	Space Science
Team Crash Racing	Sports
Toyota Circletrack Racing	Sports
Tal Control Racing	Sports
Touring Car Racer	Sports
Thrilling Customer Racing	Sports
Team Cheat Racing	Sports
Touring Car Racing	Sports