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What is trimethoprim-sulfamethoxazole mean?
Trimethoprim/sulfamethoxazole (TMP/SMX), also known as co-trimoxazole among other names, is a combination antibiotic used to treat a variety of bacterial infections. It consists of one part trimethoprim to five parts sulfamethoxazole. It is used for urinary tract infections, methicillin-resistant Staphylococcus aureus (MRSA) skin infections, travelers' diarrhea, respiratory tract infections, and cholera, among others. It may be used both to treat and prevent pneumocystis pneumonia and toxoplasmosis in people with HIV/AIDS and other causes of immunosuppression. It can be given by mouth or intravenously.
Common side effects include nausea, vomiting, rash, and diarrhea. Severe allergic reactions and Clostridium difficile infection may occasionally occur. Its use in pregnancy is not recommended. It appears to be safe for use during breastfeeding as long as the baby is healthy. TMP/SMX generally results in bacterial death. It works by blocking the making and use of folate by the microorganisms.
TMP/SMX was first sold in 1974. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2018, it was the 91st most commonly prescribed medication in the United States, with more than 8 million prescriptions.
referencePosted on 27 Oct 2024, this text provides information on Miscellaneous in Medical related to Medical. Please note that while accuracy is prioritized, the data presented might not be entirely correct or up-to-date. This information is offered for general knowledge and informational purposes only, and should not be considered as a substitute for professional advice.
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