BUD meaning in Medical ?

Answer: What is Black Urine Disease mean?

Alkaptonuria is a rare inherited genetic disease which is caused by a mutation in the HGD gene for the enzyme homogentisate 1,2-dioxygenase (EC 1.13.11.5); if a person inherits an abnormal copy from both parents (it is a recessive condition), the body accumulates an intermediate substance called homogentisic acid in the blood and tissues. Homogentisic acid and its oxidized form alkapton are excreted in the urine, giving it an unusually dark color. The accumulating homogentisic acid causes damage to cartilage (ochronosis, leading to osteoarthritis) and heart valves, as well as precipitating as kidney stones and stones in other organs. Symptoms usually develop in people over 30 years old, although the dark discoloration of the urine is present from birth.

Apart from treatment of the complications (such as pain relief and joint replacement for the cartilage damage), the drug nitisinone has been found to suppress homogentisic acid production, and research is ongoing as to whether it can improve symptoms. Alkaptonuria is a rare disease; it occurs in one in 250,000 people, but is more common in Slovakia and the Dominican Republic.

reference

Full Form	Category
Botanical Utility Droid	Academic & Science
Budapest	Airport Code
Anheuser Busch Companies, Inc. (Budweiser)	Business
Business Unit Director	Business
Bloom Under Development	Community
Buy only what you need; Use it all up; Dispose of properly	Community
Big ugly dish	Community
Bring Up Diagnostics	Computing
Back Up Dissemination	Computing
Back Up Disk	Computing
Busted Up Dog	General
Budweiser	General
Big Ugly Dog	General
BADLAPUR	Indian Railway Station
Black Urine Disease	Medical
Buruli ulcer disease	Medical
Beneficial Use Date	Military and Defence
Basic Underwater Demolition	Military and Defence
Budapest Ferenc Liszt International Airport serving Budapest, Hungary	Regional