CAST meaning in Medical ?

Answer: What is Cardiac Arrhythmia Suppression Trial mean?

The Cardiac Arrhythmia Suppression Trial (CAST) was a double-blind, randomized, controlled study designed to test the hypothesis that suppression of premature ventricular complexes (PVC) with class I antiarrhythmic agents after a myocardial infarction (MI) would reduce mortality. It was conducted between 1986 and 1989 and included over 1700 patients in 27 centres. The study found that the tested drugs increased mortality instead of lowering it as was expected. The publication of these results in 1991/92, in combination with large follow-up studies for drugs that had not been tested in CAST, led to a paradigm shift in the treatment of MI patients. Class I and III antiarrhythmics are now only used with extreme caution after MI, or they are contraindicated completely. Heart Rhythm Society Distinguished Scientist D. George Wyse was a member of the CAST trial's steering and executive committees.

reference

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中国科学技术协会	Academic & Science
Zhōngguó Kēxué Jìshù Xiéhuì	Academic & Science
Computer Assisted Statistics Textbooks	Academic & Science
Computer Assisted Statistics Teaching	Academic & Science
Cooperative Application of Science and Technology	Academic & Science
Center for Applied Sciences and Technology	Academic & Science
Campus Auxiliary Safety Team	Academic & Science
Convergence of Art, Science, and Technology	Academic & Science
Center for Applied Special Technology	Academic & Science
Center for Advanced Spatial Technologies, University of Arkansas	Academic & Science
Chinese Association for Science and Technology	Business
Commercial Aviation Safety Team	Business
Canadian Atlantic Sea Transport	Business
Carolina Actors Studio Theatre	Community
Community Actors Studio Theatre	Community
Creativity the Arts and Social Transformation	Community
Children's Aid Society of Toronto	Community
Center for Aging Services Technologies	Community
Coalition to Abolish Slavery and Trafficking	Community
Cadette And Senior Team	Community
Creative Arts Service Team	Community
Christian Actors Sharing Truth	Community
Communication, Arts, Speech, and Theater	Community
Character Always Stands Tall	Community
Catch A Special Thrill	Community
Caring And Sharing Texans	Community
Community Arts Stabilization Trust	Community
Community Action Southold Town	Community
Choral Arts Society Teens	Community
Computer Aids for Students and Teachers	Community
Computer Aided Self Teaching	Community
Children's Acting School And Theater	Community
Community And School Together	Community
Centers for Applied Science and Technology	Computing
China Academy of Space Technology	Computing
Centre for Analysis of Strategies and Technologies	Computing
China Association for Science and Technology	Computing
College of Arts, Science and Technology	Computing
Center for Advanced Spatial Technologies	Computing
Compaq Acceleration Server Technology	Computing
Consortium for Advanced Scientific and Technical	Computing
Computer Aided Simple Triage	Computing
Computer Aided Summarization Tool	Computing
College of Applied Science and Technology	Educational Institute
College of Agricultural Sciences and Technology	Educational Institute
Current Audio Signal Transmission	Electronics
Custom Array Synthesis Technology	Electronics
Carlisle Adams and Stafford Tavares	General
Come And Sit Together	General
CERN Axion Solar Telescope	General
Cosine All Sine Tangent	General
Center for Advanced Security Training	General
Contract Agents Selection Tool	General
Collaboration for Atlantic Salmon Tomorrow	General
Convoy Active Safety Technology	General
Change Average Speed To	General
Computer Aided Storage and Transport	General
Comprehensive Automotive Service Technology	General
Certified Automotive Software Tester	General
Clube Automovel de Santo Tirso	General
Curriculum Advice and Support Team	General
Chronic Addiction Substitution Treatment	General
Catch A Special Treat	General
Comfort And Support Team	General
Custom Alert System for Twitch	General
Computer-Assisted Scheme Training	General
Center for Advanced Surgical Technology	Medical
Childhood Asperger Syndrome Test	Medical
Childhood-Autism Spectrum Test	Medical
Calf Antibiotic and Sulfonamide Test	Medical
Cardiac Arrhythmia Suppression Trial	Medical
Council for Agricultural Science and Technology	Medical
Computer Assisted Supervision Team	Military and Defence
China Aerospace Science and Technology	Military and Defence
Canadian Amphibious Search Team	Military and Defence
Computer Aided Strategy Tactics	Military and Defence
Canadian Air-Sea Transportable	Regional
Computer Aided Software Testing	Softwares
Computer-assisted Survey Technology	Softwares
Computing and Systems Technology	Technology
Casey Time	Time