CFTR meaning in Medical ?

Answer: What is Cystic Fibrosis Transmembrane Conductance Regulator mean?

Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.

The CFTR gene codes for an ABC transporter-class ion channel protein that conducts chloride ions across epithelial cell membranes. Mutations of the CFTR gene affecting chloride ion channel function lead to dysregulation of epithelial fluid transport in the lung, pancreas and other organs, resulting in cystic fibrosis. Complications include thickened mucus in the lungs with frequent respiratory infections, and pancreatic insufficiency giving rise to malnutrition and diabetes. These conditions lead to chronic disability and reduced life expectancy. In male patients, the progressive obstruction and destruction of the developing vas deferens (spermatic cord) and epididymis appear to result from abnormal intraluminal secretions, causing congenital absence of the vas deferens and male infertility.

reference

Full Form	Category
Cystic Fibrosis Transmembrane Regulator	General
Citizens for the Republic	General
Cystic Fibrosis Transport Regulator	General
Central Florida Triumph Register	General
Centre de Formation du Transport Routier	General
Centre For Transport Research	General
Cystic Fibrosis Transmembrane Conductance Regulator	Medical