Effective renal plasma flow (eRPF) is a measure used in renal physiology to calculate renal plasma flow (RPF) and hence estimate renal function. The eRPF can be calculated with
e R P F = R P F × e x t r a c t i o n r a t i o {\displaystyle eRPF=RPF\times {\rm {extraction~ratio}}}where extraction ratio is the ratio of compound entering the kidney that is excreted into the final urine.
When using a compound with an extraction ratio near 1, such as para-aminohippurate (PAH), eRPF approximates RPF. Therefore, PAH clearance can be used to estimate RPF.
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