Interpersonal neurobiology (IPNB) or relational neurobiology is an interdisciplinary framework associated with human development and functioning. It was developed in the 1990s by Daniel J. Siegel who sought to bring together a wide range of scientific disciplines in demonstrating how the mind, brain, and relationships integrate to alter one another. In IPNB, the mind is viewed as a process that regulates the flow of both energy and information through its neurocircuitry, which is then shared and regulated between people through engagement, connection, and communication. Drawing on systems theory, Siegel proposed that these integrated processes within interpersonal relationships can shape the genetically programmed maturation of the nervous system. Seigel thus believes that the mind has an irreducible quality which informs his approach.
Interpersonal neurobiology also proposes that there is a substantial impact of interpersonal experiences on brain development during early developmental years. Siegel assumes that disruptions to the continuity, presence, and availability of the caregiver result in attachment disorders that manifest as physical changes in the neural structures that shape the perception of reality. The claim is that this can influence one's emotional intelligence, complexity of behaviours, and flexibility of responses later in life. IPNB is thereby argued to be a 'cause and effect' systematic interaction between genetic composition and social experiences influencing neurobiological and psychological functioning.
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