"Homer Simpson in: 'Kidney Trouble'" is the eighth episode of the tenth season of the American animated television series The Simpsons. It first aired on the Fox network in the United States on December 6, 1998. In the episode Grampa's kidneys explode, leaving him in urgent need of a donor. His son Homer initially agrees to donate one of his kidneys, but after hearing of side effects of only having one kidney, he begins to have second thoughts about the operation.
"Homer Simpson in: 'Kidney Trouble'" was directed by Mike B. Anderson and written by John Swartzwelder, although the episode's premise was pitched by former staff writer George Meyer. Meyer also pitched the sequence involving the "ship of lost souls", which received mixed reactions from The Simpsons staff members. The episode contains references to Night of the Living Dead and North by Northwest.
In its original broadcast, the episode was seen by approximately 7.2 million viewers and finished in 54th place in the ratings the week it aired. Following the release of The Simpsons - The Complete Tenth Season, "Homer Simpson in: 'Kidney Trouble'" received mixed reviews from critics.
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