MGUS meaning in Medical ?

Answer: What is Monoclonal Gammopathy of Uncertain Significance mean?

Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells secrete a myeloma protein, i.e. an abnormal antibody, into the blood; this abnormal protein is usually found during standard laboratory blood or urine tests. MGUS resembles multiple myeloma and similar diseases, but the levels of antibodies are lower, the number of plasma cells (white blood cells that secrete antibodies) in the bone marrow is lower, and it rarely has symptoms or major problems. However, since MGUS can lead to multiple myeloma, which develops at the rate of about 1.5% a year, or other symptomatic conditions, yearly monitoring is recommended.

The progression from MGUS to multiple myeloma usually involves several steps. In rare cases, it may also be related with a slowly progressive symmetric distal sensorimotor neuropathy.

reference

Full Form	Category
Monoclonal Gammopathy of Undermined Significance	General
Monoclonal Gammopathy of Undetermined Significance	Medical
Monoklonale Gammopathien Unbestimmter Signifikanz	Medical
Monoclonal Gammopathy of Unknown Significance	Medical
Monoclonal Gamopathy of Undetermined Significance	Medical
Monoclonal Gammopathy of Uncertain Significance	Medical