The Marikina Science High School (Filipino: Mataas na Paaralang Pang-Agham ng Marikina), known as MSHS or MariSci, is a Philippine public science high school (a high school using the Special Science Curriculum) located at Mayor Juan Chanyungco Street, Sta. Elena, Marikina. It is an offshoot of the Marikina Institute of Science and Technology which split up on November 9, 2001. The current principal is Ms. Janet S. Amurao, who took office on June 18, 2019 replacing Ms. Jeanette Coroza.
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