The UIS Prairie Stars (also Illinois–Springfield Prairie Stars and formerly Sangamon State University) are the athletic teams that represent the University of Illinois Springfield, located in Springfield, Illinois, in NCAA Division II intercollegiate athletics. The Prairie Stars compete as members of the East Division of the Great Lakes Valley Conference. UIS joined the GLVC in October 2008, and earned full Division II membership in August 2010.
Prior to joining the NCAA, UIS was a member of the American Midwest Conference (AMC) of the National Association of Intercollegiate Athletics (NAIA).
In 2018, both the baseball and softball programs won GLVC Conference Championships and hosted NCAA Regionals.
The UIS Baseball team has earned the number one seed in the NCAA Division II Midwest Regional in three straight seasons.
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